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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T4015 |
HG-14-10-04
|
ALK | Angiogenesis; Tyrosine Kinase/Adaptors |
HG-14-10-04 是一种特异的 ALK 抑制剂,IC50=20 nM。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-01817 |
GDF-10 Protein, Mouse, Recombinant (hFc)
growth differentiation factor |
Mouse | HEK293 Cells |
BMP-3b / GDF-10 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in mice suggest that the protein encoded by this gene plays a role in skeletal morphogenesis. In th... | |||
TMPY-01061 |
FGF-10 Protein, Human, Recombinant
fibroblast growth factor 10,KGF2 |
Human | E. coli |
Fibroblast growth factor 10 (FGF10) is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF10 exhibits mitogenic activity for keratinizing epidermal cells, but essentially no activity for fibroblasts, which is similar to the biological activity of FGF7. FGF10 pla... | |||
TMPY-06981 |
IL-1 alpha/IL-1A Protein, Human, Recombinant (E. coli)
interleukin 1 α,IL1,白介素,IL-1F1,IL1-α,IL-1A,IL1F1,白细胞介素,IL-1 ... |
Human | E. coli |
IL-1 alpha is a member of the interleukin 1 cytokine family. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions including proliferation, differentiation, and cell survival/apoptosis but are also involved in several pathophysiological processes including viral infections and autoimmune diseases. Cytokines are synthesized under various stimuli by a variety of cells of both the innate (monocytes, macrophage... | |||
TMPH-01016 |
GDF-10 Protein, Human, Recombinant (His)
|
Human | E. coli |
Growth factor involved in osteogenesis and adipogenesis. Plays an inhibitory role in the process of osteoblast differentiation via SMAD2/3 pathway. Plays an inhibitory role in the process of adipogenesis. GDF-10 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 16.1 kDa and the accession number is P55107. | |||
TMPK-00096 |
FGF-10 Protein (Primary Amine Labeling), Human, Recombinant, Biotinylated
FGF-10,KGF2 |
Human | E. coli |
Fibroblast growth factor 10 (FGF10) regulates multiple stages of structural lung morphogenesis, cellular differentiation, and the response to injury. As a driver of lung airway branching morphogenesis, FGF10 signaling defects during development lead to neonatal lung disease. Lung diseases impact patients across the lifespan, from infants in the first minutes of life through the aged population. Congenital abnormalities of lung structure can cause lung disease at birth or make adults more suscept... | |||
TMPY-01751 |
DR3/TNFRSF25 Protein, Human, Recombinant (hFc)
TRAMP,TR3,WSL-1,TNFRSF12,DR3,WSL-LR,tumor necrosis facto... |
Human | HEK293 Cells |
DR3/TNFRSF25 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 45.9 kDa and the accession number is Q93038-10. | |||
TMPY-05760 |
DR3/TNFRSF25 Protein, Human, Recombinant (hFc), Biotinylated
TRAMP,tumor necrosis factor receptor superfamily, m... |
Human | HEK293 Cells |
DR3/TNFRSF25 Protein, Human, Recombinant (hFc), Biotinylated is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 45.9 kDa and the accession number is Q93038-10. | |||
TMPY-00961 |
ADAM15 Protein, Human, Recombinant (His)
MDC15,ADAM metallopeptidase domain 15 |
Human | HEK293 Cells |
ADAM15 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 54 kDa and the accession number is Q13444-10. | |||
TMPY-02300 |
BIN1 Protein, Human, Recombinant (His)
AMPHL,bridging integrator 1,AMPH2,SH3P9 |
Human | E. coli |
Amphiphysin 2, also named bridging integrator-1 (BIN1) or SH3P9, Amphiphysin2/BIN1 is a crescent-shaped N-BAR protein playing a key role in forming deeply invaginated tubes in muscle T-tubules, has been recently implicated in rare and common diseases affecting different tissues and physiological functions. BIN1 downregulation is linked to cancer progression and also correlates with ventricular cardiomyopathy and arrhythmia preceding heart failure. Increased BIN1 expression is linked to increased... |